Dr Darren Hargrave and his team at Great Ormond Street Hospital are testing three new drugs in children with Diffuse Intrinsic Pontine Glioma (DIPG) with drugs selected.

The BIOMEDE trial, which is being funded by The Brain Tumour Charity and Cancer Research UK, will test one of three new drugs in 150 children with DIPG, over a 5 year period.

During 2015, Tina Weaving from Northants Police, contacted the popular cake company, Choccywoccydoodah to ask if they could donate a cake

for the Blue Light Boxing event raffle.

Tyronne and Ryan were so excited when they heard they were finalists in Northampton's Youth Ambition Awards 2016, and we couldn't have been more proud of them both.

Despite being forecast heavy snow, the sun was beaming on Thursday when we were presented with this incredible cheque for Alfie's Journey Fund.

December is always a hard month. Another Christmas without our Alfie Bear and reminders are everywhere.

We miss our precious Angel everyday, but even more so on occasions like Christmas.

Christmas is also a time for reflection, and as we sit back and talk over the past year, we are overwhelmed by the support that has been shown to us and the charity.

There have been so many highlights over the past 12 months. Many new supporters took on big challenges and events, and three companies kindly match funded events for us.